Cheat sheet

USMLE Step 2 CK Cheat Sheet

Practice this exam

Social Sciences and Patient Safety

  • 10-15% of exam
  • Consent, Capacity, Confidentiality Patient Safety and Quality Ethics Next Step RCA vs FMEA Capacity Four Elements

Renal, Urinary and Reproductive

  • 7-13% of exam
  • Electrolytes and Acid-Base Urology and Gynecology Rules Hyponatremia Workup Anion Gap Causes

Cardiovascular System

  • 6-12% of exam
  • BP Stages and Targets ACS and Arrhythmia Timing Heart Failure and Murmurs Chest Pain Next Step CHA2DS2-VASc Stroke Risk

Musculoskeletal, Skin and Subcutaneous

  • 6-12% of exam
  • Skin and Joint Emergencies Ortho Decision Rules SJS vs SSSS ABCDE Melanoma Check

Behavioral Health

  • 5-10% of exam
  • Psychiatry First-Line Choices Serotonin Syndrome vs NMS SIG E CAPS Depression Lithium Level Range

Blood, Lymphoreticular and Immune

  • 5-10% of exam
  • Transfusion and Coagulation Hypersensitivity and Immunodeficiency TTP vs DIC Hemoglobin 7 Threshold

Gastrointestinal System

  • 5-10% of exam
  • GI and Liver Cutoffs Crohn vs Ulcerative Colitis Lipase Three Times Normal Ascites Neutrophils 250

Nervous System and Special Senses

  • 5-10% of exam
  • Neurologic Time Windows Altered Mental Status Picker Delirium vs Dementia Thrombolysis 4.5 Hours

Respiratory System

  • 5-10% of exam
  • Pulmonary Scores and Cutoffs Acute Dyspnea Picker Transudate vs Exudate CURB-65 Admission Score

Multisystem Processes and Disorders

  • 4-8% of exam
  • Sepsis and Infection Bundles Toxicology Antidotes First Imaging Picker Sepsis Hour-1 Bundle

Endocrine System

  • 3-7% of exam
  • Diabetes and Thyroid Numbers DKA vs HHS A1C 6.5 Percent Cutoff Metformin First Line

Pregnancy, Childbirth and Puerperium

  • 3-7% of exam
  • Prenatal Care Timeline Obstetric Emergencies Bleeding in Pregnancy Previa vs Abruption Prenatal Timing Anchors

Biostatistics and Epidemiology

  • 3-5% of exam
  • Biostatistics Formulas Study Design and Bias Sensitivity vs Specificity Lead-Time vs Length-Time

Human Development and Well Care

  • 2-4% of exam
  • USPSTF Screening Ages Adult Immunization Triggers Pediatric Milestones Preventive Visit Picker

Nutrition (Double-Coded Discipline)

  • 15-20% of exam
  • Nutrition and Deficiency Clues Refeeding Syndrome Thiamine Before Glucose Double-Coded Discipline

Quick Facts

  • Exam USMLE Step 2 CK
  • Body NBME and FSMB
  • Format 16 blocks x 30 min
  • Items 316 (max 318)
  • Per block Up to 20 items
  • Session One 9-hour day
  • Break 55 minutes minimum
  • Tutorial 5-minute optional
  • Pass score 218 three-digit scale
  • Fee $695 (+$235 abroad)
  • Attempts 4 lifetime, 3 yearly
  • Pass rate 98% US MD first-takers
  • New format Effective May 7, 2026
  • Provider Prometric test centers

Capacity Four Elements SO

  • Understand, appreciate, reason, communicate a choice
  • Capacity is decision-specific Competence is a legal finding Physicians assess capacity

RCA vs FMEA SO

Root cause analysis

  • After an event
  • Finds the cause
  • Retrospective

Failure modes analysis

  • Before an event
  • Predicts failure modes
  • Prospective
  • Looks back vs forward

Ethics Next Step SO

  • Adult refuses life-saving care → Assess capacity, then honor
  • Minor requests contraception → Provide confidentially ( State laws vary )
  • Unconscious, no surrogate → Treat under implied consent
  • Family hides the diagnosis → Ask patient preference first
  • Suspected child abuse → Report to authorities ( Mandatory )
  • Colleague appears impaired → Report to supervisor
  • Threat to identified person → Warn and protect
  • Language barrier at visit → Use trained interpreter ( Not family )

Physician Task Weights SO

  • Diagnosis 16-20 percent Largest task
  • Lab/diagnostic studies 13-17 percent
  • Mixed management 12-16 percent
  • Pharmacotherapy 8-12 percent
  • Clinical interventions 6-10 percent
  • Health maintenance 5-10 percent
  • Prognosis/outcome 5-9 percent
  • Systems-based practice 5-7 percent
  • Professionalism 5-7 percent
  • Practice-based learning 3-5 percent

Clinical Science Weights SO

  • Medicine 55-65 percent Overlapping
  • Pediatrics 17-27 percent
  • Obstetrics and gynecology 10-20 percent
  • Psychiatry 10-15 percent
  • Surgery 5-15 percent
  • Why totals exceed 100 Items coded to several sciences

Consent, Capacity, Confidentiality SO

  • Capacity elements Understand, appreciate, reason, communicate
  • Emancipated minor Married, military, or parent
  • Minor consent exceptions Contraception, pregnancy, infection, substances
  • Adult refusing treatment Honor when capacity intact
  • Surrogate order Agent, spouse, adult child
  • Advance directive conflict Written directive usually controls
  • Emergency consent Implied when life threatened
  • Confidentiality exception Serious harm to others
  • Mandatory reporting Abuse and certain infections
  • Impaired colleague Report to supervisor first
  • Language barrier Use trained medical interpreter

Patient Safety and Quality SO

  • Root cause analysis Retrospective, after an event
  • Failure modes analysis Prospective, before an event
  • Swiss cheese model Aligned system holes
  • Never event Wrong-site surgery example
  • Sentinel event Serious unexpected harm
  • Error disclosure Disclose promptly and honestly
  • PDSA cycle Plan, do, study, act
  • Active error Frontline person, immediate effect
  • Latent error System or design flaw
  • Surgical time-out Verify patient, site, procedure
  • Handoff tool SBAR structured communication

Anion Gap Causes RE

  • MUDPILES for high anion gap acidosis
  • M: methanol U: uremia D: diabetic ketoacidosis P: propylene glycol I: isoniazid L: lactate E: ethylene glycol S: salicylates

Hyponatremia Workup RE

  • Any low sodium → Check serum osmolality
  • Normal serum osmolality → Consider pseudohyponatremia
  • High serum osmolality → Look for hyperglycemia
  • Low osmolality, hypovolemic → Isotonic saline
  • Low osmolality, euvolemic → Treat as SIADH ( Fluid restriction )
  • Seizure or coma → Hypertonic saline now

Electrolytes and Acid-Base RE

  • Sodium correction cap 8 mEq/L per 24 hours
  • Overcorrection risk Osmotic demyelination syndrome
  • Severe hyperkalemia Calcium gluconate first
  • Hyperkalemia ECG Peaked T waves
  • Anion gap Sodium minus chloride minus bicarbonate
  • Winter formula Expected PaCO2 in acidosis
  • Symptomatic hypercalcemia Saline, then bisphosphonate
  • Prerenal azotemia BUN/creatinine over 20
  • Acute tubular necrosis Muddy brown granular casts
  • Contrast nephropathy Prevent with isotonic saline

Urology and Gynecology Rules RE

  • Suspected kidney stone Noncontrast CT abdomen pelvis
  • Stone under 5 mm Likely passes, add tamsulosin
  • Testicular torsion Doppler ultrasound, urgent exploration
  • Pyelonephritis Culture, then empiric antibiotics
  • Abnormal uterine bleeding Exclude pregnancy first
  • Postmenopausal bleeding Endometrial biopsy required
  • Polycystic ovary syndrome Rotterdam, two of three
  • Ectopic pregnancy Abnormal hCG rise, empty uterus
  • Emergency contraception Copper IUD most effective

CHA2DS2-VASc Stroke Risk CA

  • Score 2 or more, anticoagulate
  • C: heart failure H: hypertension A2: age 75 plus D: diabetes S2: prior stroke V: vascular disease A: age 65-74 Sc: female sex

Chest Pain Next Step CA

  • ST elevation on ECG → Activate catheterization lab ( Under 90 minutes )
  • Rising troponin, no elevation → NSTEMI pathway ( Antithrombotics )
  • Tearing pain to back → CT angiography aorta ( Control blood pressure )
  • Pleuritic pain with hypoxia → CT pulmonary angiography ( Score risk first )
  • Absent breath sounds, hypotension → Needle decompression ( Do not image )
  • Burning, worse lying flat → Trial of PPI ( Reflux )
  • Reproducible wall tenderness → NSAIDs ( Costochondritis )
  • Diffuse elevation, PR depression → NSAID plus colchicine ( Pericarditis )

BP Stages and Targets CA

  • Normal Under 120/80 2025 guideline
  • Elevated Systolic 120-129, diastolic normal
  • Stage 1 130-139 or 80-89
  • Stage 2 140/90 or higher
  • Universal target Under 130/80
  • Drug trigger PREVENT risk 7.5 percent
  • First-line agents Thiazide, ACE inhibitor, CCB
  • Hypertensive emergency High BP plus organ damage
  • Emergency lowering rate About 25 percent, first hour

ACS and Arrhythmia Timing CA

  • STEMI at PCI center Balloon within 90 minutes
  • STEMI needing transfer Balloon within 120 minutes
  • No PCI available Fibrinolysis within 30 minutes
  • First ACS drugs Chewed aspirin, nitrates, heparin
  • NSTEMI marker Rising troponin, no elevation
  • Unstable tachycardia Synchronized cardioversion now
  • Stable narrow SVT Vagal, then adenosine
  • Pulseless VT or VF Defibrillate immediately
  • Torsades de pointes Intravenous magnesium sulfate
  • Atrial fibrillation stroke risk CHA2DS2-VASc 2 or more

Heart Failure and Murmurs CA

  • HFrEF pillars ARNI, beta-blocker, MRA, SGLT2
  • BNP use Rules out acute dyspnea
  • Acute pulmonary edema Oxygen, upright, intravenous furosemide
  • Aortic stenosis Crescendo-decrescendo, radiates carotids
  • Mitral regurgitation Holosystolic, radiates axilla
  • Hypertrophic cardiomyopathy Louder with Valsalva
  • Aortic regurgitation Decrescendo, wide pulse pressure
  • Mitral stenosis Opening snap, diastolic rumble
  • Cardiac tamponade Beck triad, pulsus paradoxus

ABCDE Melanoma Check MS

  • Asymmetry, Border, Color, Diameter, Evolving
  • Diameter over 6 mm Evolving matters most Excisional biopsy preferred

SJS vs SSSS MS

Stevens-Johnson

  • Mucosal erosions present
  • Drug trigger typical
  • Full-thickness necrosis

Staph scalded skin

  • Mucosa spared
  • Staph toxin mediated
  • Superficial split
  • Mucosa involved vs spared

Skin and Joint Emergencies MS

  • Septic arthritis fluid White cells over 50,000
  • Gout crystals Negatively birefringent needles
  • Pseudogout crystals Positively birefringent rhomboids
  • Stevens-Johnson syndrome Under 10 percent skin
  • Toxic epidermal necrolysis Over 30 percent skin
  • Necrotizing infection clue Pain beyond skin findings
  • Simple cellulitis Cephalexin unless MRSA suspected
  • Melanoma workup ABCDE, then excisional biopsy
  • Pemphigus vulgaris Positive Nikolsky, oral erosions
  • Toxic shock syndrome Fever, rash, later desquamation

Ortho Decision Rules MS

  • Ottawa ankle rules Tenderness or cannot bear weight
  • Compartment syndrome Pain with passive stretch
  • Scaphoid tenderness Splint despite normal x-ray
  • Open fracture Antibiotics and urgent washout
  • Elderly hip fracture Surgery within 48 hours
  • Cauda equina syndrome Urgent MRI, then decompression
  • Anterior shoulder dislocation Check axillary nerve sensation

SIG E CAPS Depression BE

  • Five symptoms, two weeks, plus core mood
  • Sleep, interest, guilt Energy, concentration Appetite, psychomotor, suicidality Need low mood or anhedonia

Serotonin Syndrome vs NMS BE

Serotonin syndrome

  • Onset within hours
  • Hyperreflexia and clonus
  • Cyproheptadine

Neuroleptic malignant

  • Onset over days
  • Lead-pipe rigidity
  • Dantrolene or bromocriptine
  • Clonus vs rigidity

Psychiatry First-Line Choices BE

  • Major depression SSRI plus psychotherapy
  • Antidepressant trial length 4 to 6 weeks
  • Bipolar mania Lithium or valproate
  • Lithium therapeutic level 0.6 to 1.2 mEq/L
  • Schizophrenia Second-generation antipsychotic
  • Treatment-resistant schizophrenia Clozapine, monitor neutrophils
  • Alcohol withdrawal Benzodiazepines, symptom-triggered
  • Opioid use disorder Buprenorphine or methadone
  • Panic disorder SSRI plus cognitive therapy
  • Active suicidal intent Ensure safety, hospitalize

TTP vs DIC HE

TTP

  • Normal PT and PTT
  • ADAMTS13 deficiency
  • Plasma exchange

DIC

  • Prolonged PT and PTT
  • Low fibrinogen
  • Treat underlying cause
  • Clotting times normal vs prolonged

Transfusion and Coagulation HE

  • Stable transfusion threshold Hemoglobin under 7 g/dL
  • Prophylactic platelets Count under 10,000
  • Febrile nonhemolytic reaction Fever, chills, no hemolysis
  • Acute hemolytic reaction ABO mismatch, stop transfusion
  • TRALI Hypoxia within 6 hours
  • Microcytic anemia Check iron studies first
  • Warfarin reversal Four-factor PCC, vitamin K
  • Heparin reversal Protamine sulfate
  • Suspected HIT Stop heparin, start argatroban
  • Suspected DVT Compression ultrasound of leg

Hypersensitivity and Immunodeficiency HE

  • Type I IgE, immediate anaphylaxis
  • Type II Antibody against cell surface
  • Type III Immune complex deposition
  • Type IV T cell, delayed onset
  • Anaphylaxis first drug Intramuscular epinephrine, lateral thigh
  • Recurrent sinopulmonary infection Check immunoglobulin levels
  • Asplenia risk Encapsulated organism sepsis

Crohn vs Ulcerative Colitis GI

Crohn disease

  • Mouth to anus
  • Skip lesions
  • Transmural, fistulas

Ulcerative colitis

  • Rectum extending proximally
  • Continuous involvement
  • Mucosa only
  • Skip lesions vs continuous

GI and Liver Cutoffs GI

  • Upper GI bleed Endoscopy within 24 hours
  • Variceal bleed Octreotide plus ceftriaxone
  • Acute pancreatitis Lipase three times normal
  • Right upper quadrant pain Ultrasound is first test
  • Ascending cholangitis Charcot triad, urgent ERCP
  • Spontaneous bacterial peritonitis Ascites neutrophils over 250
  • Hepatic encephalopathy Lactulose, then rifaximin
  • Adult appendicitis CT with contrast
  • C. difficile colitis Oral vancomycin or fidaxomicin
  • Celiac testing Tissue transglutaminase IgA

Delirium vs Dementia NE

Delirium

  • Acute onset
  • Attention impaired
  • Often reversible

Dementia

  • Months to years
  • Memory affected first
  • Progressive course
  • Attention vs memory

Altered Mental Status Picker NE

  • Any altered patient → Check glucose first
  • Pinpoint pupils, slow breathing → Give naloxone
  • Fever with neck stiffness → Cultures, then antibiotics ( Do not delay )
  • Sudden focal deficit → Noncontrast head CT ( Stroke pathway )
  • Alcohol use with confusion → Thiamine before glucose
  • Fluctuating attention, acute onset → Treat delirium cause
  • Seizure with low sodium → Hypertonic saline bolus

Neurologic Time Windows NE

  • Intravenous thrombolysis Within 4.5 hours onset
  • Thrombectomy Up to 24 hours, selected
  • First stroke test Noncontrast head CT
  • Thunderclap headache CT, then lumbar puncture
  • Status epilepticus Intravenous lorazepam first
  • Bacterial meningitis Antibiotics before delayed imaging
  • Giant cell arteritis Steroids before biopsy
  • Myasthenic crisis Follow vital capacity
  • Normal pressure hydrocephalus Gait, incontinence, dementia
  • Wernicke encephalopathy Confusion, ataxia, eye findings

CURB-65 Admission Score RE

  • Confusion, Urea, Respirations, BP, age 65
  • Urea above 19 Respirations 30 or more Systolic under 90 Score 2, consider admission

Transudate vs Exudate RE

Transudate

  • Pressure problem
  • Heart failure, cirrhosis
  • Low protein

Exudate

  • Inflammation or infection
  • Meets Light criteria
  • High LDH
  • Pressure vs inflammation

Acute Dyspnea Picker RE

  • Wheeze with known asthma → Albuterol and steroids
  • Fever with purulent sputum → Treat pneumonia ( CURB-65 triage )
  • Crackles with high BNP → Intravenous diuresis ( Heart failure )
  • Pleuritic, tachycardic, hypoxic → Evaluate for embolism
  • Stridor and drooling → Secure the airway ( Do not examine throat )
  • Hypoxia after transfusion → Stop transfusion ( Consider TRALI )
  • Hyperresonance with hypotension → Needle decompression

Pulmonary Scores and Cutoffs RE

  • CURB-65 of 2 Consider hospital admission
  • Low PE probability Apply PERC rule
  • D-dimer role Rules out low-probability embolism
  • PE confirmation CT pulmonary angiography
  • Asthma exacerbation Albuterol, ipratropium, systemic steroids
  • COPD exacerbation Bronchodilators, steroids, antibiotics
  • COPD diagnosis Post-bronchodilator FEV1/FVC under 0.70
  • Light criteria Protein or LDH ratio
  • ARDS oxygenation PaO2/FiO2 under 300
  • Tension pneumothorax Decompress before imaging

Sepsis Hour-1 Bundle MU

  • Lactate, cultures, antibiotics, fluids, pressors
  • Cultures before antibiotics 30 mL/kg crystalloid Norepinephrine first Remeasure the lactate

First Imaging Picker MU

  • Right upper quadrant pain → Abdominal ultrasound ( Gallstones )
  • Suspected appendicitis, adult → CT with contrast
  • Suspected appendicitis, child → Ultrasound first ( Limit radiation )
  • Flank pain with hematuria → Noncontrast CT ( Stones )
  • Head trauma, red flags → Noncontrast head CT
  • Thunderclap headache → Noncontrast head CT ( Then lumbar puncture )
  • Unstable blunt abdominal trauma → Bedside FAST ultrasound
  • Stable suspected dissection → CT angiography
  • Acute testicular pain → Doppler ultrasound ( Torsion )
  • Suspected pulmonary embolism → CT pulmonary angiography

Sepsis and Infection Bundles MU

  • Sepsis definition Infection plus organ dysfunction
  • Antibiotics in shock Within 1 hour
  • Initial fluid 30 mL/kg crystalloid, 3 hours
  • MAP target 65 mmHg or higher
  • First vasopressor Norepinephrine
  • Lactate Remeasure when above 2
  • Adult meningitis empiric Vancomycin plus ceftriaxone
  • Add ampicillin Age over 50, listeria
  • Necrotizing fasciitis Surgical debridement, not imaging

Toxicology Antidotes MU

  • Acetaminophen N-acetylcysteine
  • Opioid Naloxone
  • Benzodiazepine Flumazenil, seizure risk
  • Organophosphate Atropine plus pralidoxime
  • Beta-blocker overdose Glucagon, then calcium
  • Calcium channel blocker High-dose insulin, calcium
  • Methanol or ethylene glycol Fomepizole plus dialysis
  • Carbon monoxide 100 percent oxygen
  • Iron Deferoxamine
  • Digoxin Digoxin-specific antibody fragments
  • Salicylate Bicarbonate, then dialysis

DKA vs HHS EN

DKA

  • Glucose often over 250
  • Anion gap acidosis
  • Ketones strongly positive

HHS

  • Glucose often over 600
  • Osmolality over 320
  • Minimal ketones
  • Acidosis vs osmolality

Diabetes and Thyroid Numbers EN

  • Diabetes A1C 6.5 percent or higher
  • Fasting glucose 126 mg/dL or higher
  • Two-hour OGTT 200 mg/dL or higher
  • Prediabetes A1C 5.7 to 6.4 percent
  • Usual adult A1C goal Under 7 percent
  • Type 2 first line Metformin plus lifestyle
  • Heart or kidney disease Add SGLT2 or GLP-1
  • DKA hallmark Anion gap plus ketones
  • Primary hypothyroidism High TSH, low T4
  • Thyroid nodule workup TSH, then ultrasound

Prenatal Timing Anchors PR

  • Anatomy 20, glucose 26, strep 36
  • Anatomy scan 18-22 weeks Glucose challenge 24-28 weeks Group B strep 36-37 weeks Tdap 27-36 weeks

Previa vs Abruption PR

Placenta previa

  • Painless bleeding
  • Ultrasound before exam
  • No digital exam

Abruption

  • Painful bleeding
  • Rigid tender uterus
  • Largely clinical diagnosis
  • Painless vs painful

Bleeding in Pregnancy PR

  • First trimester bleeding → Ultrasound and hCG
  • Empty uterus, elevated hCG → Treat as ectopic
  • Painless third-trimester bleeding → Ultrasound before exam ( Previa )
  • Painful bleeding, rigid uterus → Prepare for delivery ( Abruption )
  • Postpartum bleeding, boggy uterus → Massage plus oxytocin
  • Rh-negative mother bleeding → Give anti-D globulin
  • Membrane rupture with bleeding → Emergency cesarean ( Vasa previa )

Prenatal Care Timeline PR

  • Dating ultrasound First trimester most accurate
  • Cell-free fetal DNA From 10 weeks
  • Nuchal translucency 11-14 weeks
  • Quad screen 15-22 weeks
  • Anatomy ultrasound 18-22 weeks
  • Glucose challenge 24-28 weeks, 50 grams
  • Anti-D immune globulin 28 weeks and postpartum
  • Tdap dose 27-36 weeks each pregnancy
  • Group B strep culture 36w0d to 37w6d
  • Antibody screen First visit, repeat 28 weeks

Obstetric Emergencies PR

  • Preeclampsia BP 140/90 twice, 4 hours apart
  • Severe-range BP 160/110 or higher
  • Severe-feature labs Platelets under 100,000
  • Eclampsia treatment Magnesium sulfate, then delivery
  • Aspirin prophylaxis 81 mg from 12 weeks
  • Magnesium toxicity Lost reflexes, give calcium
  • Postpartum hemorrhage Uterine atony most common
  • Shoulder dystocia McRoberts, suprapubic pressure
  • Chorioamnionitis Antibiotics and deliver

Sensitivity vs Specificity BI

Sensitivity

  • Detects disease
  • Negative rules out
  • Good for screening

Specificity

  • Confirms disease
  • Positive rules in
  • Good for confirmation
  • Rule out vs rule in

Biostatistics Formulas BI

  • Sensitivity True positives among diseased
  • Specificity True negatives among well
  • Positive predictive value Rises with prevalence
  • Negative predictive value Falls as prevalence rises
  • Relative risk Cohort and trial designs
  • Odds ratio Case-control designs
  • Absolute risk reduction Control risk minus treated
  • Number needed to treat One over absolute reduction
  • Incidence New cases over time
  • Prevalence All existing cases now
  • Positive likelihood ratio Higher value, stronger test
  • Type I error False positive, alpha
  • Type II error False negative, beta
  • Power One minus beta

Study Design and Bias BI

  • Randomized trial Strongest causal evidence
  • Cohort study Exposure first, follow forward
  • Case-control study Outcome first, look backward
  • Cross-sectional study Snapshot, yields prevalence
  • Lead-time bias Earlier diagnosis, unchanged death
  • Length-time bias Screening favors slow tumors
  • Confounding Third variable distorts association
  • Recall bias Case-control interview error
  • Berkson bias Hospital-based selection problem
  • Intention to treat Analyze as randomized

Preventive Visit Picker HU

  • Woman turning 40 → Offer biennial mammography
  • Adult turning 45 → Start colorectal screening
  • Smoker aged 50 to 80 → Annual low-dose CT ( 20 pack-years )
  • Man 65-75 who smoked → One-time aortic ultrasound
  • Woman turning 65 → Order DXA scan
  • Adult 35-70 with obesity → Screen for diabetes

USPSTF Screening Ages HU

  • Mammography Biennial, ages 40-74 2024
  • Colorectal screening Ages 45 through 75 2021
  • Cervical cytology Every 3 years, 21-29
  • Cervical age 30-65 hrHPV every 5 years
  • Lung low-dose CT Annual, ages 50-80 20 pack-years
  • Lung quit rule Quit within 15 years
  • Aortic aneurysm Men 65-75 who smoked One-time
  • Osteoporosis DXA Women 65 and older 2025
  • Diabetes screening Ages 35-70 with overweight
  • HIV screening Once, ages 15-65
  • Hepatitis C Once, ages 18-79
  • Statin primary prevention 40-75, risk 10 percent
  • Depression and anxiety Screen all adults
  • Prostate PSA Shared decision, ages 55-69

Adult Immunization Triggers HU

  • Tdap in pregnancy Every pregnancy, 27-36 weeks
  • Influenza Annual from 6 months
  • Recombinant zoster Two doses, age 50
  • Pneumococcal conjugate All adults 50 and older
  • HPV series Routine 11-12, catch-up 26
  • Td booster Every 10 years
  • RSV vaccine Single dose, age 75
  • Hepatitis B All adults 19-59

Pediatric Milestones HU

  • 2 months Social smile
  • 6 months Sits supported, babbles
  • 9 months Pulls to stand, stranger anxiety
  • 12 months First words, walks alone
  • 18 months Runs, several single words
  • 2 years Two-word phrases, climbs stairs
  • 3 years Tricycle, copies circle
  • 4 years Hops, copies cross
  • 5 years Skips, copies triangle

Nutrition and Deficiency Clues NU

  • Nutrition weighting 15-20 percent, double-coded Overlaps systems
  • Refeeding syndrome Low phosphate, magnesium, potassium
  • Thiamine before glucose Prevents Wernicke encephalopathy
  • Vitamin B12 deficiency Macrocytic with neurologic signs
  • Folate deficiency Macrocytic, nerves spared
  • Vitamin D deficiency Low calcium, high PTH
  • Vitamin K deficiency Prolonged PT and INR
  • Zinc deficiency Poor healing, perioral rash
  • Vitamin A deficiency Night blindness, dry eyes

Common Traps

Capacity vs competence

  • Physicians assess capacity ≠ Courts decide competence

Screening vs diagnosis

  • Screening finds risk ≠ Diagnosis confirms disease

Sensitivity vs predictive value

  • Sensitivity ignores prevalence ≠ PPV depends on prevalence

Retrospective vs prospective analysis

  • RCA looks backward ≠ FMEA looks forward

DKA vs HHS

  • DKA has acidosis ≠ HHS has extreme osmolality

Previa vs abruption

  • Previa bleeding is painless ≠ Abruption bleeding is painful

Lead-time vs length-time bias

  • Lead-time shifts diagnosis earlier ≠ Length-time favors slow tumors

Delirium vs dementia

  • Delirium impairs attention ≠ Dementia impairs memory

Folate vs B12 deficiency

  • Both cause macrocytosis ≠ Only B12 harms nerves

Gout vs pseudogout crystals

  • Gout has negative birefringence ≠ Pseudogout has positive birefringence

Nutrition weighting confusion

  • Nutrition is double-coded ≠ Systems already total 100

Block count vs item count

  • Sixteen 30-minute blocks now ≠ Item total is unchanged

Last Minute

  • 1. Sixteen 30-minute blocks, 9-hour day
  • 2. Up to 20 items per block
  • 3. 55 minutes break, 5-minute tutorial
  • 4. Passing score is 218
  • 5. Fee $695; $235 outside US/Canada
  • 6. Three attempts yearly, four lifetime
  • 7. Report 30 minutes before start
  • 8. Bring unexpired photo-signature ID
  • 9. Social sciences is largest system
  • 10. Diagnosis tasks are 16-20 percent
  • 11. Mammography 40-74; colon from 45
  • 12. Lung CT 50-80, 20 pack-years
  • 13. Blood pressure target under 130/80
  • 14. Stroke thrombolysis within 4.5 hours
  • 15. Septic shock antibiotics within 1 hour
  • 16. Raise sodium under 8 daily
  • 17. Transfuse when hemoglobin under 7
  • 18. Check glucose in every confusion
  • 19. Group B strep culture 36-37 weeks
  • 20. Capacity is decision-specific, not global

USMLE Step 2 CK

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