ABIM Med Oncology

Practice session

A 54-year-old postmenopausal woman has a 2.2 cm, grade 2, ER 95%, PR 80%, HER2 0 by IHC, Ki-67 15% invasive ductal carcinoma with 1 of 3 sentinel nodes positive. Oncotype DX recurrence score is 18. In addition to breast-conserving therapy with whole-breast radiation, which adjuvant systemic therapy is most appropriate?

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