Anatomic Pathology Board

Practice session

An autopsy on a 68-year-old man who died of cardiogenic shock following an acute myocardial infarction reveals a wedge-shaped, pale, firm area in the left kidney. Microscopic examination of this renal lesion demonstrates preservation of the basic tissue architecture with intact structural outlines of glomeruli and tubules ('ghost outlines'), but with total loss of nuclear staining (karyolysis and pyknosis) and increased cytoplasmic eosinophilia. Neutrophilic infiltration is present at the periphery. Which pattern of necrosis is this?

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